The composition of our global workforce continues to evolve. Our strategic focus on business growth in Emerging Markets has meant the workforce in these areas has grown substantially (as shown in the Sales and Marketing workforce composition figures below). This increase has been accompanied by headcount reductions as a result of our continuing strategic drive to improve efficiency and effectiveness. Reductions have come about through restructuring in R&D, supply and manufacturing, support functions and our sales and marketing workforce in Established Markets, together with the disposal of our Astra Tech business. The net effect of these changes since the end of 2006 has been to reduce our total headcount by some 9,600 from 66,800 to 57,200. This decrease includes a reduction of 2,600 positions in 2010 and a further 5,000 in 2011 which resulted from our business change plans announced in 2010.
Sales and Marketing workforce composition

In 2011, the most significant business change was the implementation of the R&D strategy announced in 2010, which also involved a number of site changes. While the net impact by the end of 2011 was a reduction of approximately 1,400 roles, almost all R&D employees worldwide were impacted in some way by this change. In order to mitigate further job losses, over 750 employees were redeployed where appropriate skills and capabilities allowed. We were committed to ensuring that AstraZeneca’s core values, robust people policies, consultation infrastructure and prior experience were integrated into this multi-faceted business transformation. Trade unions and employee representative groups were involved throughout the restructuring process. With significant investment in outplacement support, high levels of success have been achieved in finding employees alternative opportunities outside AstraZeneca.
In addition, there were reductions in the number of roles in several areas of our sales and marketing organisation in 2011, which were incremental to the ongoing restructuring programme announced in 2010. The most substantial reduction was in the US, where we announced in December that the sales force would be reduced by approximately 1,150 leadership positions and sales representative roles by the end of February 2012.
In February 2012, we announced the next phase of restructuring. Further details are set out in the Our strategic priorities to 2014 section.
We work to ensure a level of global consistency in managing employee relations, while allowing enough flexibility to support the local markets in building good relations with their workforces, taking into account local laws and circumstances. To that end, relations with trade unions are nationally determined and managed locally in line with the applicable legal framework and standards of good practice. However, each change programme has its unique challenges and a standard solution may not always be appropriate. Where this is the case, the appropriate solution is developed through consultation with employee representatives or, where applicable, trade unions, with the aim of retaining key skills and mitigating job losses.