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Our year in brief

Summary financial and operational information for 2010

Financial Highlights

 

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Operational Overview

 

92 92 projects in clinical development, including 9 in Phase III or under regulatory review. 34 withdrawn during the year 7% Revenue in the US fell 7%, while revenue in Rest of World rose by 7% $5bn Annual Crestor and Seroquel sales exceeded $5 billion each
$5.1bn Revenue in Emerging Markets grew to over $5.1 billion, a 16% increase $2.4bn The first phase of the restructuring programme is now complete, resulting in annual benefits of $2.4 billion $2.1bn Net share repurchases totalled $2.1 billion in 2010
  • Single R&D organisation in place, including new leadership team, global organisation structure and governance framework
  • Vimovo approved in the US and the EU; Brilique approved in the EU with Complete Response Letter received for Brilinta in the US; Kombiglyze XRTM (OnglyzaTM/metformin combination) approved in the US; decisions made in December to discontinue development of motavizumab and Certriad
  • Completed a deal with Rigel for the Phase III development of fostamatinib (for rheumatoid arthritis), and TC-5214, our neuroscience collaboration with Targacept, also entered Phase III development
  • Agreement with HealthCore, which maintains the largest commercially insured population data environment in the US, enables real world studies of health outcomes
  • Portfolio of more than 100 generic products being licensed across 30 Emerging Markets for marketing under our brand
  • Crestor substance patent upheld in the US courts
  • Ranked in the top 8% in the sector in the Dow Jones Sustainability World and European Indexes
  • Reviewed and revised Responsible Business Plan to align it with strategic business priorities
  • Additional ways of reporting sales and marketing performance introduced to support increased transparency
  • Improvement in senior leader communications with employees but slight decline in employee engagement
 

All growth rates are at CER

Product performance summary



Arimidex

$1,512m -22%

(2009: $1,921m; 2008: $1,857m)

Atacand

$1,483m +3%

(2009: $1,436m; 2008: $1,471m)

Crestor

$5,691m +24%

(2009: $4,502m; 2008: $3,597m)

Nexium

$4,969m 0%

(2009: $4,959m; 2008: $5,200m)

Seloken/Toprol-XL

$1,210m -17%

(2009: $1,443m; 2008: $807m)

Seroquel IR

$4,148m -1%

(2009: $4,171m; 2008: $4,223m)

Seroquel XR

$1,154m +67%

(2009: $695m; 2008: $229m)

Symbicort

$2,746m +20%

(2009: $2,294m; 2008: $2,004m)

Synagis

$1,038m -4%

(2009: $1,082m; 2008: $1,230m)

Zoladex

$1,115m 0%

(2009: $1,086m; 2008: $1,138m)