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Notes to the Financial Statements (Group)

2 Operating profit

Operating profit includes the following items:

Selling, general and administrative costs

AstraZeneca is defending its interests in various federal and state investigations and civil litigation matters relating to drug marketing and pricing practices and in respect of which the Company has made provisions in aggregate of $636m during 2009. $524m of this has been made in respect of the US Attorney's Office investigation into sales and marketing practices involving Seroquel and $112m relates to average wholesale price litigation. The current status of these matters is described in Note 25. These provisions constitute our best estimate at the time of losses expected for these matters.

Other operating income and expense

2009
$m
2008
$m
2007
$m
Royalties
Income 255 288 236
Amortisation (79) (84) -
Impairment (150) (91) -
Net gain on disposal of property, plant and equipment 8 6 9
Gains on disposal of product rights 170 - -
Net gain/(loss) on disposal of other intangible assets 1 (17) (1)
Gains on divestments of non-core products 216 118 192
Impairment of intangible assets relating to future licensing and contractual income (115) - -
Other income 265 304 310
Other expense (18) - (18)
Other operating income and expense 553 524 728

Royalty amortisation relates to income streams acquired with MedImmune. The amortisation in 2007 ($53m) was posted to SG&A and not adjusted.

Restructuring and synergy costs

During 2009 the Group continued the restructuring and synergy programmes approved by the SET and announced in 2007 and 2008. In addition, the Group announced further programmes during the year. The tables below show the costs that have been charged in respect of these programmes by cost category and type. Severance provisions are detailed in Note 18.

2009
$m
2008
$m
2007
$m
Cost of sales 188 405 415
Research and development 68 166 73
Selling, general and administrative costs 403 310 478
Total charge 659 881 966
2009
$m
2008
$m
2007
$m
Severance costs 262 499 678
Accelerated depreciation and impairment 148 219 203
Other 249 163 85
Total charge 659 881 966

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AstraZeneca Annual Report and Form 20-F Information 2009

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