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Directors’ Remuneration Report

John Varley

“We have included in our work during 2008 an extensive benchmarking of the activities and policies of the Remuneration Committee to assess how these conform with the continuous advance in best practice in these areas. Our objective in this work, as in all our work, is to ensure that AstraZeneca’s remuneration strategy supports its business strategy, and thereby serves shareholders.”

JOHN VARLEY
Chairman of the Remuneration Committee

This Directors’ Remuneration Report has been prepared in accordance with the Directors’ Remuneration Report Regulations 2002 (the Regulations) and meets the relevant requirements of the Financial Services Authority’s (FSA) Listing Rules. As required by the Regulations, a resolution to approve the report will be proposed at the Annual General Meeting (AGM) on 30 April 2009.

The following sections of the Directors’ Remuneration Report up to and including the section titled Non-Executive Directors were not subject to audit by KPMG Audit Plc.

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