AstraZeneca Annual Report and Form 20-F Information 2008

Auditor's Reports on the Financial Statements and on Internal Control over Financial Reporting (Sarbanes-Oxley Act Section 404)

The report set out below is provided in compliance with International Standards on Auditing (UK and Ireland). KPMG Audit Plc has also issued reports in accordance with auditing standards of the Public Company Accounting Oversight Board in the US, which will be included in the Annual Report on Form 20-F to be filed with the US Securities and Exchange Commission. Those reports are unqualified and include opinions on the Financial Statements and on the effectiveness of internal control over financial reporting as at 31 December 2008 (Sarbanes-Oxley Act Section 404). The Directors’ statement on internal control over financial reporting is set out in the Directors' Responsibilities for, and Report on, Internal Control over Financial Reporting.

KPMG Audit Plc has also reported separately on the Company Financial Statements of AstraZeneca PLC and on the information in the Directors’ Remuneration Report that is described as having been audited. This audit report is set out in the Independent Auditor’s Report to the Members of AstraZeneca PLC (Company).