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Financial performance 2008/2007

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OUR FINANCIAL PERFORMANCE

 
2008 2007  2006 2008 compared to 2007 2007 compared to 2006 
  
  
  
  
  
  
Sales 
$m 
  
CER 
growth 
$m 
Growth 
due to 
exchange 
effect 
$m 
  
  
Sales 
$m 
  
CER 
growth 
$m 
Growth 
due to 
exchange 
effect 
$m 
  
  
Sales 
$m 
  
CER 
growth 
  
Reported 
growth 
  
CER 
growth 
  
Reported 
growth 
Seloken/Toprol-XL 807 (667) 36 1,438 (393) 36 1,795 (46) (44) (22) (20)
Crestor 3,597 714  87 2,796 673  95 2,028 26  29  33  38 
Atacand 1,471 123  61 1,287 99  78 1,110 10  14  16 
Plendil 268 (18) 15 271 (20) 16 275 (7) (1) (7) (1)
Tenormin 313 (17) 22 308 (24) 12 320 (6) (8) (4)
Zestril 236 (72) 13 295 (30) 18 307 (24) (20) (10) (4)
Other 271 (34) 14 291 (14) 22 283 (12) (7) (5)
Total 6,963 29  248 6,686 291  277 6,118 – 

PERFORMANCE 2008

Reported performance

CV sales were up 4% as reported to $6,963 million (2007: $6,686 million). Strong growth from Crestor, fuelled by the promotion of the atherosclerosis indication and increased sales of Atacand offset the continuing significant declines in Seloken/Toprol-XL.

Performance – CER growth rates

CV sales were unchanged from 2007 at CER. Crestor sales increased by 26% to $3,597 million. US sales for Crestor for the full year increased by 18% to $1,678 million. Crestor total prescription share in the US statin market increased to 9.9% in December 2008 from 8.6% in December 2007, and was the only branded statin to gain market share. Crestor sales in the Rest of World were up 34% for the full year to $1,919 million, over half of global sales for the product. Sales were up 16% in Western Europe to $836 million and 93% in Japan driving sales growth in the Established Markets and the Rest of World up 33% in total. Sales in Emerging Markets increased by 41%.

Toprol-XL and authorised generic sales of the drug in the US were down 70% for the full year to $295 million. For the full year, Seloken sales in the Rest of World were up 1% to $512 million.

US sales for Atacand for the full year increased 1% to $262 million. Sales in other markets were up 12% to $1,209 million, on a 10% increase in Established Markets and an 18% increase in Emerging Markets.

PERFORMANCE 2007

Reported performance

CV sales rose by 9% from $6,118 million in 2006 to $6,686 million in 2007. Continued strong growth from Crestor more than offset the significant declines in Seloken/Toprol-XL.

Performance – CER growth rates

CV sales grew by 5% at CER. Crestor sales increased by 33% to $2,796 million. In the US, Crestor sales for the full year were $1,424 million, a 24% increase over 2006. Total prescriptions in the US statin market increased 8% for the year; Crestor prescriptions were up 22%. Sales outside the US for the full year increased 45% to $1,372 million, nearly half the total worldwide sales for the product. Sales were up 26% in Western Europe with good growth in France and Italy. Sales in Canada increased 43%.

Global sales of Seloken/Toprol-XL fell by 22% to $1,438 million. US sales of the Toprol-XL product range, which includes sales of the authorised generic were down 30% for the full year, as the full range of dosage strengths were subject to generic competition from August 2007. Sales of Seloken in other markets were up 5% for the full year as a result of growth in Emerging Markets.

Atacand sales in the US were unchanged for the full year whilst sales in other markets increased 12%.

Continued small declines were seen in Zestril (down 10% to $295 million) and Plendil (down 7% to $271 million), with general global falls compensated by increases in discrete markets.

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