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Financial Statements

Principal Subsidiaries

At 31 December 2007 Country Percentage of voting share capital held Principal activity
UK
AstraZeneca UK Limited England 1001 Research and development, manufacturing, marketing
AstraZeneca Reinsurance Limited England 100 Insurance and reinsurance underwriting
AstraZeneca Treasury Limited England 100 Treasury
Continental Europe
NV AstraZeneca SA Belgium 100 Manufacturing, marketing
AstraZeneca Dunkerque Production SCS France 100 Manufacturing
AstraZeneca SAS France 100 Research, manufacturing, marketing
AstraZeneca GmbH Germany 100 Development, manufacturing, marketing
AstraZeneca Holding GmbH Germany 100 Manufacturing, marketing
AstraZeneca SpA Italy 100 Manufacturing, marketing
AstraZeneca Farmaceutica Spain SA Spain 100 Manufacturing, marketing
AstraZeneca AB Sweden 100 Research and development, manufacturing, marketing
AstraZeneca BV The Netherlands 100 Marketing
The Americas
AstraZeneca Canada Inc. Canada 100 Research, manufacturing, marketing
IPR Pharmaceuticals Inc. Puerto Rico 100 Development, manufacturing, marketing
AstraZeneca LP US 99 Research and development, manufacturing, marketing
AstraZeneca Pharmaceuticals LP US 100 Research and development, manufacturing, marketing
Zeneca Holdings Inc. US 100 Manufacturing, marketing
MedImmune, Inc. US 100 Research and development, manufacturing, marketing
Asia, Africa & Australasia
AstraZeneca Pty Limited Australia 100 Development, manufacturing, marketing
AstraZeneca KK Japan 80 Manufacturing, marketing

1Shares held directly.

The companies and other entities listed above are those whose results or financial position principally affected the figures shown in the Group Financial Statements. A full list of subsidiaries, joint ventures and associates will be annexed to the Company’s next annual return filed with the Registrar of Companies. The country of registration or incorporation is stated alongside each company. The accounting year ends of subsidiaries and associates are 31 December, except for Aptium Oncology, Inc. which, owing to local conditions and to avoid undue delay in the preparation of the Financial Statements, is 30 November. AstraZeneca operates through 290 subsidiaries worldwide. The Group Financial Statements consolidate the Financial Statements of the Company and its subsidiaries at 31 December 2007. Products are manufactured in 20 countries worldwide and are sold in over 100 countries.

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