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Additional information

Percentage analysis at 31 December 2007 of issued share capital

By size of account
No. of shares
2007
%
1 – 250 0.5
251 – 500 0.7
501 – 1,000 0.9
1,001 – 5,000 1.3
5,001 – 10,000 0.2
10,001 – 50,000 1.0
50,001 – 1,000,000 12.9
Over 1,000,0001 82.5
Issued share capital 100.0

1Includes VPC and ADR holdings.

At 31 December 2007, AstraZeneca PLC had 133,820 registered holders of 1,457,000,853 Ordinary Shares of $0.25 each. At 31 December 2007, there were approximately 223,000 holders of American Depositary Receipts (ADRs) representing 9.58% of the issued share capital and 145,000 holders of shares held under the VPC Services Agreement representing 20.55% of the issued share capital. The ADRs, each of which is equivalent to one Ordinary Share, are issued by JPMorgan Chase Bank.

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