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Additional information

Major shareholdings

At 31 January 2008, the following had disclosed an interest in the issued Ordinary Share capital of the Company in accordance with the requirements of section 5.1.2 of the UK Listing Authority’s Disclosure and Transparency Rules:

Shareholder Number of shares Date of
disclosure
to Company*
Percentage
of issued
share capital
Capital Research and Management Company 71,261,060 25 Jun 2007 4.89%
Axa SA 70,934,559 20 Dec 2007 4.87%
Investor AB 63,465,810 11 Feb 2004 4.36%
Barclays PLC 61,721,820 18 Dec 2006 4.24%
Wellington Management Co., LLP 60,565,299 30 Oct 2006 4.16%
Legal & General Investment Management Limited 59,198,535 12 Sept 2007 4.06%

* Since the date of disclosure to the Company, the interest of any person listed above in the Ordinary Shares of the Company may have increased or decreased. No requirement to notify the Company of any increase or decrease would have arisen unless the holding moved up or down through a whole number percentage level. The percentage level may increase (on the cancellation of shares following a re-purchase of shares under the Company’s share re-purchase programme) or decrease (on the issue of new shares under any of the Company’s share plans).

No other person held a notifiable interest in shares, comprising 3% or more of the issued Ordinary Share capital of the Company.

Changes in the percentage ownership held by major shareholders during the past three years are set out below. Major shareholders do not have different voting rights.

  Percentage of issued share capital
Shareholder 31 Jan 2008 31 Jan 2007 31 Jan 2006 26 Jan 2005
Capital Research and Management Company 4.89% 11.70% 12.57% 13.39%
Axa SA 4.87%
Investor AB 4.36% 4.14% 4.01% 3.86%
Barclays PLC 4.24% 4.03% 3.20% 3.08%
Wellington Management Co., LLP 4.16% 3.95% 4.97% 3.25%
Legal & General Investment Management Limited 4.06% 3.43% 3.32% 3.19%

AstraZeneca PLC American Depositary Shares (each representing one Ordinary Share) evidenced by American Depositary Receipts issued by JPMorgan Chase Bank, as depositary, are listed on the New York Stock Exchange. At 31 January 2008, the proportion of Ordinary Shares represented by American Depositary Shares was 9.58% of the Ordinary Shares outstanding.

Number of registered holders of Ordinary Shares at 31 January 2008:

Number of record holders of American Depositary Receipts at 31 January 2008:

So far as the Company is aware, it is neither directly nor indirectly owned nor controlled by one or more corporations or by any government.

At 31 January 2008, the total amount of the Company’s voting securities owned by Directors and Officers of the Company was:

Title of class Amount owned Percentage of class
Ordinary Shares 283,176 0.02%

The Company does not know of any arrangements, the operation of which might result in a change in the control of the Company.

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